2010, ISBN: 1420059971

Edição encadernada

[EAN: 9781420059977], Gebraucht, sehr guter Zustand, [PU: CRC Press], MEDICAL TOXICOLOGY MOLECULAR BIOLOGY ADDUCT FORMATION ARSENIC APO MT ACCUMULATION ACTIVITY ADHESION AMINO ACID APOPTO… mais…

[EAN: 9781420059977], Gebraucht, sehr guter Zustand, [PU: CRC Press], MEDICAL TOXICOLOGY MOLECULAR BIOLOGY ADDUCT FORMATION ARSENIC APO MT ACCUMULATION ACTIVITY ADHESION AMINO ACID APOPTOSIS BALLATORI BASOLATERAL UPTAKE MEMBRANE BILE BILIARY BINDING BLOOD BUTHIONINE SULFOXIMINE BSO CADHERINS CADMIUM CALCIUM CANALICULAR CATION CELLULAR CHELATORS COMPLEXES CONCENTRATIONS COPPER CYTOSOLIC CELL DISRUPTION MOLECULES CERULOPLASMIN DISEASE DMPS DMT1 EFFECTS ENTEROCYTES ENZYMES EPITHELIAL CELLS EXCRETION EXPOSURE EXPRESSION DIFFUSION ENDOSOMAL LYSOSOMAL VESICLES FERRITIN FERROPORTIN FUNCTION GENE GLUTATHIONE GAP JUNCTIONS GSH HEAVY METALS HEMOCHROMATOSIS HEPATIC HEPATOCYTES HEPCIDIN HOMEOSTASIS HUMAN INCREASED INDUCED INHIBITION INORGANIC MERCURY INTEGRIN INTERACTION INTESTINAL INTRACELLULAR INVOLVED IRON OVERLOAD HEAT SHOCK PROTEINS HSPS METABOLISM HEME EXPORT MICROANATOMY TRANSPORT PERMEATION HEPATOPANCREAS HEPHAESTIN HEREDITARY IMMUNE MECHANISMS SYSTEM IMMUNOMODULATION ASSESSMENT IMMUNOTOXIC INTESTINE SEQUESTRATION THIOLS KIDNEY KINASE LEAD LEVELS LIGANDS LIVER LUMINAL LYSOSOMES PHARMACOLOGICAL CONSIDERATIONS PLASMA MANGANESE MECHANISM MEDIATED MERCURIC CHLORIDE CONJUGATES IONS METAL METALLOTHIONEIN METHYLMERCURY MICE MITOCHONDRIA MITOCHONDRIAL MOUSE MRP2 MUTATIONS MANGANISM RECYCLING RENAL HANDLING TRAFFICKING ORGANIC ANION TRANSPORTER OXIDATIVE STRESS PATHWAY PHARMACOL PROXIMAL TUBULAR REACTION RECEPTOR REDOX REGULATION ROLE SIGNALING SPECIFIC STUDIES TISSUE TOXICITY TRANSFERRIN TUBULE ZINC FUNCTIONING NEPHRONS SOLUTE CARRIERS OXYANIONS, **Price reduction until 31/09/2023** Oversized hardcover, x + 430 pages, NOT ex-library. Weight 956g (please note: extra shipping will be required). Missing the title page (neatly removed). Faint non-sticky glue residue inside the front board (a gently removed sticker). Interior is clean, crisp and bright, with unmarked text, free of inscriptions and stamps, firmly bound. Boards show a touch of shelfwear. Issued without a dust jacket. -- With chapter contributions from more than 30 metal biology experts, Cellular and Molecular Biology of Metals explains the role of key divalent metal ions involved in the molecular and cellular biology of various target cell populations. Although it primarily focuses on homeostatic metals, such as nickel, zinc, and chromium, the text also discusses a few environmentally pertinent, toxic divalent cations, including mercury, cadmium, and arsenic. This authoritative resource reviews the physiological mechanisms underlying the handling of essential and toxic metal ions, including metal ion homeostasis, metals and enzyme activity, metals and transcriptional regulation, and metal ion transport. It also analyzes other functions designed to avoid metal-induced toxicity and mediate the metal enhancement of cellular function. The role of metal ions and their effect on mammalian cells and organs are only beginning to be truly defined. Cellular and Molecular Biology of Metals arms metals toxicologists and cellular and molecular biologists with the necessary knowledge they need to take the research effort to the next level. -- Contents: 1. Cellular Inorganic Chemistry Concepts and Examples 2. Molecular and Cellular Biology of Mercury in the Kidneys 3. Essential and Toxic Metal Transport in the Liver 4. Molecular and Cell Biology of Lead 5. Transport and Biological Impact of Manganese 6. Metallothionein and Metal Homeostasis 7. Cellular and Molecular Biology of Iron-Binding Proteins 8. Regulatory and Signaling Functions of Zinc Ions in Human Cellular Physiology 9. Glutathione, Protein Thiols, and Metal Homeostasis 10. Ionic and Molecular Mimicry and the Transport of Metals 11. Heavy Metal Transport and Detoxification in Crustacean Gastrointestinal and Renal Epithelial Cells 12. Metals and Cell Adhesion Molecules 13. Iron Metabolism and Disease 14. Metal Influences on Immune Function; Index, Books<