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Enhancement of solubility of Mebendazole by SEDDS | Self Emulsifying Drug Delivery System of Mebendazole with improved solubility, effective against lymphatic filariasis | Naveen Patel (u. a.) | Buch - Patel, Naveen
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Patel, Naveen:

Enhancement of solubility of Mebendazole by SEDDS | Self Emulsifying Drug Delivery System of Mebendazole with improved solubility, effective against lymphatic filariasis | Naveen Patel (u. a.) | Buch - Livro de bolso

2012, ISBN: 9783659116339

[ED: Taschenbuch], [PU: LAP Lambert Academic Publishing], The aim of the present work was to prepare Self emulsifying drug delivery system (SEDDS) of a lipophilic drug, Mebendazole for in… mais…

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Enhancement of solubility of Mebendazole by SEDDS / Self Emulsifying Drug Delivery System of Mebendazole with improved solubility, effective against lymphatic filariasis / Naveen Patel (u. a.) / Buch - Patel, Naveen
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Patel, Naveen:

Enhancement of solubility of Mebendazole by SEDDS / Self Emulsifying Drug Delivery System of Mebendazole with improved solubility, effective against lymphatic filariasis / Naveen Patel (u. a.) / Buch - Livro de bolso

2012, ISBN: 9783659116339

[ED: Taschenbuch], [PU: LAP Lambert Academic Publishing], The aim of the present work was to prepare Self emulsifying drug delivery system (SEDDS) of a lipophilic drug, Mebendazole for in… mais…

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Enhancement of solubility of Mebendazole by SEDDS - Naveen Patel|Aparna Lanka
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Enhancement of solubility of Mebendazole by SEDDS - Livro de bolso

2012

ISBN: 3659116335

[EAN: 9783659116339], Neubuch, [PU: LAP LAMBERT Academic Publishing], MEDIZIN PHARMAZIE MEBENDAZOLE SELF EMULSIFYING DRUG DELIVERY TOCOPHEROL ACETATE PEG 200 LABRASOL, Dieser Artikel ist … mais…

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Enhancement of solubility of Mebendazole by SEDDS - Naveen Patel Aparna Lanka
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Enhancement of solubility of Mebendazole by SEDDS - encadernada, livro de bolso

2012, ISBN: 9783659116339

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Lanka, Aparna,Patel, Naveen:
Enhancement of solubility of Mebendazole by SEDDS: Self Emulsifying Drug Delivery System of Mebendazole with improved solubility, effective against lymphatic filariasis - Livro de bolso

2012, ISBN: 9783659116339

LAP LAMBERT Academic Publishing, 2012-06-23. Paperback. Good. 0.7480 in x 8.4252 in x 5.8661 in., LAP LAMBERT Academic Publishing, 2012-06-23, 2.5

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Enhancement of solubility of Mebendazole by SEDDS: Self Emulsifying Drug Delivery System of Mebendazole with improved solubility, effective against lymphatic filariasis
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Número ISBN:

3659116335


The aim of the present work was to prepare Self emulsifying drug delivery system (SEDDS) of a lipophilic drug, Mebendazole for increasing its solubility. Various oils, surfactants and co-surfactants were screened for their suitability in the formulation of SEDDS. Based on the initial screening, Omix of Tocopherol acetate and Peceol in the ratio 6:4 and surfactant, Labrasol and co-surfactant, PEG 200 were found to be satisfactory. Five formulations were selected from pseudoternary phase diagrams and were evaluated for parameters like drug content, percentage transmittance, dilution potential, centrifugation test, in-vitro release study, emulsification time and dispersibility, emulsion droplet size, zeta potential, polydispersibility index and ex-vivo permeation studies. All the formulations exhibited a rapid emulsification rate and a good polydispersibity index. The size of the droplets as determined by zeta sizer was found to be below 300 nm. The percentage drug release from the formulations was improved compared to that of pure drug. Thus, the formulated SEDDS helped in improving the solubility and dissolution of the drug, thereby increasing its therapeutic effectiveness.

Dados detalhados do livro - Enhancement of solubility of Mebendazole by SEDDS: Self Emulsifying Drug Delivery System of Mebendazole with improved solubility, effective against lymphatic filariasis


EAN (ISBN-13): 9783659116339
ISBN (ISBN-10): 3659116335
Livro de capa dura
Livro de bolso
Ano de publicação: 2012
Editor/Editora: LAP LAMBERT Academic Publishing

Livro na base de dados desde 2008-12-03T08:42:46-02:00 (Sao Paulo)
Página de detalhes modificada pela última vez em 2023-11-08T17:02:57-03:00 (Sao Paulo)
Número ISBN/EAN: 3659116335

Número ISBN - Ortografia alternativa:
3-659-11633-5, 978-3-659-11633-9
Ortografia alternativa e termos de pesquisa relacionados:
Autor do livro: patel, lanka
Título do livro: solubilities, enhancement, solubility

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