2010, ISBN: 1617374873

".interesting and thought provoking, but technically challenging.excellent guide to current research techniques in the field of phosphodiesterase.". Rechnung legen wir bei. Dies gilt insb… mais…

".interesting and thought provoking, but technically challenging.excellent guide to current research techniques in the field of phosphodiesterase.". Rechnung legen wir bei. Dies gilt insbesondere wenn eine ISBN durch den Verlag doppelt vergeben wurde. Phosphodiesterase Methods and ProtocolsEinbandPaperback / SoftbackAutor(en)Lugnier, ClaireVerlagSpringer, BerlinAusgabe2010Formatangaben336 pages; 336 p. 93 illus., 1 illus. in color.; 229 x 152 mmSpracheengISBN1617374873ISBN-13 / EAN9781617374876Reihe / SerieMethods in Molecular Biology 307SchlagworteCalcium, hybridization, Filtration, Lipid, Nucleotide, Promoter, Termination, genes, Escherichia coliPreisEUR 106,99 (inkl. MwSt.)NEUWARE - Tagesaktueller, sicherer und weltweiter Versand. Rechnung legen wir bei.Advanced Methods to Investigate the Role ofPDEs in Intracellular SignalingThe multigenic family of cyclic nucleotide phosphodiesterases (PDEs) is now known to offer many new therapeutic possibilities through their influence over intracellular signaling, though their precise cell mechanisms to modulating that process remain uncertain. In Phosphodiesterase Methods and Protocols, a panel of research leaders in the PDE field describes new concepts and techniques for investigating the role of PDEs in orchestrating normal and pathophysiological responses. Presented in step-by-step detail, these readily reproducible methods allow the measurement of cyclic nucleotide variations in living cells, as well as their visualization in a spatiotemporal manner, the localization and characterization of their activities in tissues and living cells, and the assessment of targeted PDEs in creating specific tools and drugs. Additional chapters discuss the generation of PDE4 knockout mice to demonstrate not only the potential role of targeted PDEs, but also their use in further studies of the central role of PDE regulation in intracellular signaling control. These techniques offer clinicians a way to find new therapies for numerous pathologies whose molecular origins are unknown and whose treatment is symptomatic. Alterations of intracellular signaling related to PDE deregulation in such pathologies as inflammation, neurodegeneration, and cancer may explain the difficulties observed in their prevention and treatment. The protocols follow the successful Methods in Molecular Biology(TM) series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Path-breaking and highly practical, Phosphodiesterase Methods and Protocols offers cell biologists, molecular biologists, pharmacologists, and medicinal chemists a broad ranging survey of the advanced tools and concepts needed to understand the role of PDEs in physiological functions, their implications in several critical pathologies, and the opportunities they offer for new drug design."...interesting and thought provoking, but technically challenging...excellent guide to current research techniques in the field of phosphodiesterase." - Doody's Health Sciences Book Review JournalHinweis: Auflage und/oder Erscheinungsjahr können im Buchkatalog von eBay unter Umständen von unseren Angeboten abweichen. Dies gilt insbesondere wenn eine ISBN durch den Verlag doppelt vergeben wurde. Im Einzelfall bzw. bei Bedarf bitte VOR Bestellung erfragen.Angaben zur Versandzeit stammen aus Standardeinstellung von ebay; Wir verschicken tagesaktuell; Sendungen unter 1 kg werden als Waren-/Büchersendung (Laufzeiten sind leider sehr unterschiedlich zwischen 2 und 14 Werktagen) verschickt, ab 1 Kg erfolgt der Versand über DPD.Falls Sie eine Bestellung dringend bzw. zu einem bestimmten Zeitpunkt benötigen, wählen Sie bitte immer die Versandart PAKETVERSAND (DPD Classic), ansonsten können wir die Lieferzeiten nicht garantieren.Artikel eingestellt mit dem w+h GmbH eBay-ServiceDaten- und Bilderhosting mit freundlicher Unterstützung von Buchfreund. (2023-04-02), Festpreisangebot, [LT: FixedPrice], EAN: 9781617374876, Buchtitel: Phosphodiesterase Methods and Protocols 1234, Sprache: Englisch, Format: 336 pages; 336 p. 93 illus., 1 illus. in color.; 229 x 152 mm, Produktart: Paperback / Softback, Anzahl der Seiten: 336 pages, Gewicht: 494g, 2010<

2010, ISBN: 1617374873

[EAN: 9781617374876], Neubuch, [PU: Humana Press Inc.], This item is printed on demand. New copy - Usually dispatched within 5-9 working days, Books

2010, ISBN: 9781617374876

Buch, Softcover, Softcover reprint of hardcover 1st ed. 2005, [PU: Humana Press Inc.], Humana Press Inc., 2010

2010, ISBN: 1617374873

[EAN: 9781617374876], Neubuch, [PU: Humana Press], 336 pages. 9.25x6.10x0.80 inches. In Stock., Books

2010, ISBN: 9781617374876

Edição encadernada

Softcover reprint of hardcover 1st ed. 2005, Softcover, Buch, [PU: Humana Press Inc.]