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RNA interference Screens as a Tool for Discovering Gene Function - Despina Siolas
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Despina Siolas:

RNA interference Screens as a Tool for Discovering Gene Function - Livro de bolso

2016, ISBN: 9783843375092

[ED: Taschenbuch], [PU: LAP LAMBERT Academic Publishing], Neuware - Recent advances in the field of RNA interference (RNAi) have enabled researchers to conduct in depth investigations of … mais…

Custos de envio:Versand nach Deutschland. (EUR 2.40) AHA-BUCH GmbH
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RNA interference Screens as a Tool for Discovering Gene Function : for cancer genetics studies - Despina Siolas
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Despina Siolas:

RNA interference Screens as a Tool for Discovering Gene Function : for cancer genetics studies - Livro de bolso

2010, ISBN: 3843375097

[EAN: 9783843375092], Neubuch, [PU: LAP LAMBERT Academic Publishing], nach der Bestellung gedruckt Neuware - Printed after ordering - Recent advances in the field of RNA interference (RNA… mais…

NEW BOOK. Custos de envio:Versandkostenfrei. (EUR 0.00) AHA-BUCH GmbH, Einbeck, Germany [51283250] [Rating: 5 (von 5)]
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RNA interference Screens as a Tool for Discovering Gene Function : for cancer genetics studies - Despina Siolas
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Despina Siolas:
RNA interference Screens as a Tool for Discovering Gene Function : for cancer genetics studies - Livro de bolso

2010

ISBN: 3843375097

[EAN: 9783843375092], Neubuch, [PU: LAP LAMBERT Academic Publishing], nach der Bestellung gedruckt Neuware -Recent advances in the field of RNA interference (RNAi) have enabled researcher… mais…

NEW BOOK. Custos de envio:Versandkostenfrei. (EUR 0.00) AHA-BUCH GmbH, Einbeck, Germany [51283250] [Rating: 5 (von 5)]
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RNA interference Screens as a Tool for Discovering Gene Function
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RNA interference Screens as a Tool for Discovering Gene Function - nuovo livro

ISBN: 9783843375092

Recent advances in the field of RNA interference (RNAi) have enabled researchers to conduct in depth investigations of gene function using RNAi libraries. Our second-generation shRNA libr… mais…

Nr. GSTVLB7EUGG. Custos de envio:, Lieferzeit: 5 Tage, DE. (EUR 0.00)
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RNA interference Screens as a Tool for Discovering Gene Function for cancer genetics studies - Siolas, Despina
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Siolas, Despina:
RNA interference Screens as a Tool for Discovering Gene Function for cancer genetics studies - nuovo livro

2010, ISBN: 3843375097

Kartoniert / Broschiert, mit Schutzumschlag neu, [PU:LAP Lambert Acad. Publ.]

Custos de envio:Versandkostenfrei innerhalb der BRD. (EUR 0.00) MARZIES.de Buch- und Medienhandel, 14621 Schönwalde-Glien

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RNA interference Screens as a Tool for Discovering Gene Function

Recent advances in the field of RNA interference (RNAi) have enabled researchers to conduct in depth investigations of gene function using RNAi libraries. Our second-generation shRNA libraries consist of over 200,000 short hairpin RNA constructs targeting over 45,000 human and mouse genes modeled after primary miRNA transcripts. Each hairpin is linked to a unique 60 nucleotide identification sequence, which serves as a barcode and allows us to virtually count the number of cells that contain a specific hairpin in a cell population. Small changes in barcode copy number can be monitored through the use of microarray technology. The barcode can be amplified from a cell's genomic DNA and fluorescently labeled to produce a probe that is hybridized to a microarray. I applied this RNAi barcode screening method in a screen using a complex mixture of 7500 library hairpins in a p53 isogenic HCT 116 colon cancer cells to identify genes that modify sensitivity to a common chemotherapeutic, doxorubicin. This work illustrates the powerful use of RNAi screens to search for genes that synergize with existing therapeutics, and suggests strategies for genetically informed combination therapies.

Dados detalhados do livro - RNA interference Screens as a Tool for Discovering Gene Function


EAN (ISBN-13): 9783843375092
ISBN (ISBN-10): 3843375097
Livro de capa dura
Livro de bolso
Ano de publicação: 2010
Editor/Editora: LAP Lambert Acad. Publ.
208 Páginas
Peso: 0,326 kg
Língua: eng/Englisch

Livro na base de dados desde 2007-11-14T10:53:10-02:00 (Sao Paulo)
Página de detalhes modificada pela última vez em 2023-04-22T04:24:12-03:00 (Sao Paulo)
Número ISBN/EAN: 9783843375092

Número ISBN - Ortografia alternativa:
3-8433-7509-7, 978-3-8433-7509-2
Ortografia alternativa e termos de pesquisa relacionados:
Título do livro: interference, cancer


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