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ISBN: 9781617378478

Extensive research has uncovered a set of molecular surveillance mechanisms - commonly called "checkpoints" - which tightly monitor cell-cycle processes. Today''s anti… mais…

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ISBN: 9781617378478

Extensive research has uncovered a set of molecular surveillance mechanisms - commonly called "checkpoints" - which tightly monitor cell-cycle processes. Today''s anticancer drug developm… mais…

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Checkpoint Responses in Cancer Therapy - Livro de bolso

2010

ISBN: 9781617378478

Extensive research has uncovered a set of molecular surveillance mechanisms – commonly called “checkpoints” – which tightly monitor cell-cycle proc… mais…

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Checkpoint Responses in Cancer Therapy - nuovo livro

ISBN: 9781617378478

Extensive research has uncovered a set of molecular surveillance mechanisms - commonly called "checkpoints" - which tightly monitor cell-cycle processes. Today''s anticancer dru… mais…

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Checkpoint Responses in Cancer Therapy - Livro de bolso

ISBN: 9781617378478

Paperback, [PU: Humana Press Inc.], Checkpoint Responses in Cancer Therapy summarizes the advances made over the past 20 years, identifying components of cell-cycle checkpoints and their … mais…

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Checkpoint Responses in Cancer Therapy by Wei Dai Paperback | Indigo Chapters

Extensive research has uncovered a set of molecular surveillance mechanisms - commonly called "checkpoints" - which tightly monitor cell-cycle processes. Today's anticancer drug development has identified many of these cell-cycle checkpoint molecules as effective targets. Research now promises to uncover a new generation of anticancer drugs with improved therapeutic indices based on their ability to target emerging checkpoint components. Checkpoint Responses in Cancer Therapy summarizes the advances made over the past 20 years, identifying components of cell-cycle checkpoints and their molecular regulation during checkpoint activation and validating the use of checkpoint proteins as targets for the development of anticancer drugs. This book's distinguished panel of authors takes a close look at topics ranging from the major molecular players affecting DNA synthesis and the response to DNA damage to advances made in the identification of chemical compounds capable of inhibiting individual mitotic kinases. Illuminating and authoritative, Checkpoint Responses in Cancer Therapy offers a critical summary of findings for researchers in the pharmaceutical and biotechnology industries and a valuable resource for academic scientists in cancer research and the study of cell-cycle regulation, signal transduction and apoptosis.

Dados detalhados do livro - Checkpoint Responses in Cancer Therapy by Wei Dai Paperback | Indigo Chapters


EAN (ISBN-13): 9781617378478
ISBN (ISBN-10): 161737847X
Livro de bolso
Ano de publicação: 2010
Editor/Editora: Wei Dai
328 Páginas
Peso: 0,494 kg
Língua: eng/Englisch

Livro na base de dados desde 2012-03-14T18:55:53-03:00 (Sao Paulo)
Página de detalhes modificada pela última vez em 2022-10-07T14:29:45-03:00 (Sao Paulo)
Número ISBN/EAN: 9781617378478

Número ISBN - Ortografia alternativa:
1-61737-847-X, 978-1-61737-847-8
Ortografia alternativa e termos de pesquisa relacionados:
Autor do livro: wei
Título do livro: checkpoint


Dados da editora

Autor: Wei Dai
Título: Cancer Drug Discovery and Development; Checkpoint Responses in Cancer Therapy
Editora: Humana; Humana Press
314 Páginas
Ano de publicação: 2010-11-19
Totowa; NJ; US
Impresso / Feito em
Peso: 0,504 kg
Língua: Inglês
213,99 € (DE)
219,99 € (AT)
236,00 CHF (CH)
POD
XIV, 314 p. 33 illus., 3 illus. in color.

BC; Cancer Research; Hardcover, Softcover / Medizin/Nichtklinische Fächer; Onkologie; Verstehen; DNA; apoptosis; biotechnology; cancer; cancer research; cancer therapy; cell; cell cycle; checkpoint; chemotherapy; development; drug; drug design; drug development; research; Pharmacology/Toxicology; Cancer Biology; Pharmacology; Pharmakologie; BB

Preface Action of the RB pathway in response to therapeutic agents Erik S. Knudsen Targeting the p53/MDM2 pathway for cancer therapy Lyubomir T. Vassilev DNA topoisomerases as targets for the chemotherapeutic treatment of cancer Neil Osheroff Targeting the DNA damage checkpoint (ATM/ATR) Wafik S. El-Deiry (Not in yet) Compounds that abrogate the G2 checkpoint Takumi Kawabe CDK inhibitors as anti-cancer agents J. de Bono CHFR as a potential anti-cancer target T. Tokino Antimicrotubule agents M. Villalona-Calero Kinesin motor inhibitors as effective anti-cancer drugs A. Giannis Targeting the spindle checkpoint in cancer chemotherapy Hongtao Yu Anti-proliferation inhibitors targeting aurora kinases Daruka Mahadevan Plks as novel targets for cancer drug design Wei Dai Do histone deacetylase inhibitors target cell cycle checkpoints that monitor heterochromatin structure? Brian G. Gabrielli

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