The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkab… mais…
The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkable achievements in the field and to illustrate how beneficial these studies can be for the advancement of both basic knowledge on biological regulation and deregulation and for the clinical treatment of a wide spectrum of diseases. This goal is attained by contributions of leader investigators in the field, who address the issue from different angles. TOC:From the Contents.- Protein Kinase Inhibitors for the Treatment of Disease; the Promise and the Problems.- Part 1: General Aspects of PKs Inhibition.- New Design Strategies for Ligands that Target Protein Kinase Mediated Protein-Protein Interactions.- Part 2: Pharmacological Potential and Inhibitors of Individual Classes of Protein Kinases.- The Paullones, a Family of Pharmacological Inhibitors of Cyclin-Dependent Kinases and Glycogen Synthase Kinase -3. Pharmacological Potential of p38 MAPK Inhibitors. Inhibitors of PKA and Related Protein Kinases. Inhibitors of Protein Kinase CK2: Structural Aspects. Aminoglycoside Kinases and Antibiotic Resistance.- Part 3: Pharmacological Potential and Inhibitors of Individual Classes of Protein Phosphatases.- Protein Tyrosine Phosphatases as Therapeutic Targets. Structure-Based Design of PTP Inhibitors. Biological Validation of the CD45 Tyrosine Phosphatase as a Pharmaceutical Target. Serine/Threonine Protein Phosphatase Inhibitors with Antitumor Activity.- Part 4: Inhibitors in Clinical Use or Advanced Clinical Trials.- Clinical Immunosuppression Using the Calcineurin-Inhibitors Ciclosporin and Tacrolimus. Targeted Therapy with Imatinib: An Exception or a Rule? Clinical Aspects of Imantinib Therapy. Isoquinolinesulfonamide, a Specific Inhibitor of Rho-Kinase and the Clinical Aspect of Anti-Rho-Kinase Therapy. Discovery and Development of Iressa - The First in a New Class of Drugs Targeted at the Epidermal Growth Factor Receptor Tyrosine Kinase. eBook Springer PDF, Springer, 30.03.2006, Springer, 2006<
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The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkab… mais…
The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkable achievements in the field and to illustrate how beneficial these studies can be for the advancement of both basic knowledge on biological regulation and deregulation and for the clinical treatment of a wide spectrum of diseases. This goal is attained by contributions of leader investigators in the field, who address the issue from different angles. TOC:From the Contents.- Protein Kinase Inhibitors for the Treatment of Disease; the Promise and the Problems.- Part 1: General Aspects of PKs Inhibition.- New Design Strategies for Ligands that Target Protein Kinase Mediated Protein-Protein Interactions.- Part 2: Pharmacological Potential and Inhibitors of Individual Classes of Protein Kinases.- The Paullones, a Family of Pharmacological Inhibitors of Cyclin-Dependent Kinases and Glycogen Synthase Kinase -3. Pharmacological Potential of p38 MAPK Inhibitors. Inhibitors of PKA and Related Protein Kinases. Inhibitors of Protein Kinase CK2: Structural Aspects. Aminoglycoside Kinases and Antibiotic Resistance.- Part 3: Pharmacological Potential and Inhibitors of Individual Classes of Protein Phosphatases.- Protein Tyrosine Phosphatases as Therapeutic Targets. Structure-Based Design of PTP Inhibitors. Biological Validation of the CD45 Tyrosine Phosphatase as a Pharmaceutical Target. Serine/Threonine Protein Phosphatase Inhibitors with Antitumor Activity.- Part 4: Inhibitors in Clinical Use or Advanced Clinical Trials.- Clinical Immunosuppression Using the Calcineurin-Inhibitors Ciclosporin and Tacrolimus. Targeted Therapy with Imatinib: An Exception or a Rule? Clinical Aspects of Imantinib Therapy. Isoquinolinesulfonamide, a Specific Inhibitor of Rho-Kinase and the Clinical Aspect of Anti-Rho-Kinase Therapy. Discovery and Development of Iressa - The First in a New Class of Drugs Targeted at the Epidermal Growth Factor Receptor Tyrosine Kinase. eBook Springer PDF, Springer, 30.03.2006, Springer, 2006<
Thalia.de
Nr. 24485740. Custos de envio:, Sofort per Download lieferbar, DE. (EUR 0.00) Details...
(*) Livro esgotado significa que o livro não está disponível em qualquer uma das plataformas associadas buscamos.
The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkab… mais…
The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkable achievements in the field and to illustrate how beneficial these studies can be for the advancement of both basic knowledge on biological regulation and deregulation and for the clinical treatment of a wide spectrum of diseases. This goal is attained by contributions of leader investigators in the field, who address the issue from different angles. TOC:From the Contents.- Protein Kinase Inhibitors for the Treatment of Disease; the Promise and the Problems.- Part 1: General Aspects of PKs Inhibition.- New Design Strategies for Ligands that Target Protein Kinase Mediated Protein-Protein Interactions.- Part 2: Pharmacological Potential and Inhibitors of Individual Classes of Protein Kinases.- The Paullones, a Family of Pharmacological Inhibitors of Cyclin-Dependent Kinases and Glycogen Synthase Kinase -3. Pharmacological Potential of p38 MAPK Inhibitors. Inhibitors of PKA and Related Protein Kinases. Inhibitors of Protein Kinase CK2: Structural Aspects. Aminoglycoside Kinases and Antibiotic Resistance.- Part 3: Pharmacological Potential and Inhibitors of Individual Classes of Protein Phosphatases.- Protein Tyrosine Phosphatases as Therapeutic Targets. Structure-Based Design of PTP Inhibitors. Biological Validation of the CD45 Tyrosine Phosphatase as a Pharmaceutical Target. Serine/Threonine Protein Phosphatase Inhibitors with Antitumor Activity.- Part 4: Inhibitors in Clinical Use or Advanced Clinical Trials.- Clinical Immunosuppression Using the Calcineurin-Inhibitors Ciclosporin and Tacrolimus. Targeted Therapy with Imatinib: An Exception or a Rule? Clinical Aspects of Imantinib Therapy. Isoquinolinesulfonamide, a Specific Inhibitor of Rho-Kinase and the Clinical Aspect of Anti-Rho-Kinase Therapy. Discovery and Development of Iressa - The First in a New Class of Drugs Targeted at the Epidermal Growth Factor Receptor Tyrosine Kinase. eBook Springer 30.03.2006, Springer, Springer<
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Nr. 24485740. Custos de envio:, Sofort per Download lieferbar, zzgl. Versandkosten. (EUR 16.85) Details...
(*) Livro esgotado significa que o livro não está disponível em qualquer uma das plataformas associadas buscamos.
The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkab… mais…
The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkable achievements in the field and to illustrate how beneficial these studies can be for the advancement of both basic knowledge on biological regulation and deregulation and for the clinical treatment of a wide spectrum of diseases. This goal is attained by contributions of leader investigators in the field, who address the issue from different angles. TOC:From the Contents.- Protein Kinase Inhibitors for the Treatment of Disease; the Promise and the Problems.- Part 1: General Aspects of PKs Inhibition.- New Design Strategies for Ligands that Target Protein Kinase Mediated Protein-Protein Interactions.- Part 2: Pharmacological Potential and Inhibitors of Individual Classes of Protein Kinases.- The Paullones, a Family of Pharmacological Inhibitors of Cyclin-Dependent Kinases and Glycogen Synthase Kinase -3. Pharmacological Potential of p38 MAPK Inhibitors. Inhibitors of PKA and Related Protein Kinases. Inhibitors of Protein Kinase CK2: Structural Aspects. Aminoglycoside Kinases and Antibiotic Resistance.- Part 3: Pharmacological Potential and Inhibitors of Individual Classes of Protein Phosphatases.- Protein Tyrosine Phosphatases as Therapeutic Targets. Structure-Based Design of PTP Inhibitors. Biological Validation of the CD45 Tyrosine Phosphatase as a Pharmaceutical Target. Serine/Threonine Protein Phosphatase Inhibitors with Antitumor Activity.- Part 4: Inhibitors in Clinical Use or Advanced Clinical Trials.- Clinical Immunosuppression Using the Calcineurin-Inhibitors Ciclosporin and Tacrolimus. Targeted Therapy with Imatinib: An Exception or a Rule? Clinical Aspects of Imantinib Therapy. Isoquinolinesulfonamide, a Specific Inhibitor of Rho-Kinase and the Clinical Aspect of Anti-Rho-Kinase Therapy. Discovery and Development of Iressa - The First in a New Class of Drugs Targeted at the Epidermal Growth Factor Receptor Tyrosine Kinase. eBook Springer PDF, Springer, 30.03.2006, Springer, 2006<
Nr. 24485740. Custos de envio:, Sofort per Download lieferbar, DE. (EUR 0.00)
The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkab… mais…
The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkable achievements in the field and to illustrate how beneficial these studies can be for the advancement of both basic knowledge on biological regulation and deregulation and for the clinical treatment of a wide spectrum of diseases. This goal is attained by contributions of leader investigators in the field, who address the issue from different angles. TOC:From the Contents.- Protein Kinase Inhibitors for the Treatment of Disease; the Promise and the Problems.- Part 1: General Aspects of PKs Inhibition.- New Design Strategies for Ligands that Target Protein Kinase Mediated Protein-Protein Interactions.- Part 2: Pharmacological Potential and Inhibitors of Individual Classes of Protein Kinases.- The Paullones, a Family of Pharmacological Inhibitors of Cyclin-Dependent Kinases and Glycogen Synthase Kinase -3. Pharmacological Potential of p38 MAPK Inhibitors. Inhibitors of PKA and Related Protein Kinases. Inhibitors of Protein Kinase CK2: Structural Aspects. Aminoglycoside Kinases and Antibiotic Resistance.- Part 3: Pharmacological Potential and Inhibitors of Individual Classes of Protein Phosphatases.- Protein Tyrosine Phosphatases as Therapeutic Targets. Structure-Based Design of PTP Inhibitors. Biological Validation of the CD45 Tyrosine Phosphatase as a Pharmaceutical Target. Serine/Threonine Protein Phosphatase Inhibitors with Antitumor Activity.- Part 4: Inhibitors in Clinical Use or Advanced Clinical Trials.- Clinical Immunosuppression Using the Calcineurin-Inhibitors Ciclosporin and Tacrolimus. Targeted Therapy with Imatinib: An Exception or a Rule? Clinical Aspects of Imantinib Therapy. Isoquinolinesulfonamide, a Specific Inhibitor of Rho-Kinase and the Clinical Aspect of Anti-Rho-Kinase Therapy. Discovery and Development of Iressa - The First in a New Class of Drugs Targeted at the Epidermal Growth Factor Receptor Tyrosine Kinase. eBook Springer PDF, Springer, 30.03.2006, Springer, 2006<
Nr. 24485740. Custos de envio:, Sofort per Download lieferbar, DE. (EUR 0.00)
The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkab… mais…
The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkable achievements in the field and to illustrate how beneficial these studies can be for the advancement of both basic knowledge on biological regulation and deregulation and for the clinical treatment of a wide spectrum of diseases. This goal is attained by contributions of leader investigators in the field, who address the issue from different angles. TOC:From the Contents.- Protein Kinase Inhibitors for the Treatment of Disease; the Promise and the Problems.- Part 1: General Aspects of PKs Inhibition.- New Design Strategies for Ligands that Target Protein Kinase Mediated Protein-Protein Interactions.- Part 2: Pharmacological Potential and Inhibitors of Individual Classes of Protein Kinases.- The Paullones, a Family of Pharmacological Inhibitors of Cyclin-Dependent Kinases and Glycogen Synthase Kinase -3. Pharmacological Potential of p38 MAPK Inhibitors. Inhibitors of PKA and Related Protein Kinases. Inhibitors of Protein Kinase CK2: Structural Aspects. Aminoglycoside Kinases and Antibiotic Resistance.- Part 3: Pharmacological Potential and Inhibitors of Individual Classes of Protein Phosphatases.- Protein Tyrosine Phosphatases as Therapeutic Targets. Structure-Based Design of PTP Inhibitors. Biological Validation of the CD45 Tyrosine Phosphatase as a Pharmaceutical Target. Serine/Threonine Protein Phosphatase Inhibitors with Antitumor Activity.- Part 4: Inhibitors in Clinical Use or Advanced Clinical Trials.- Clinical Immunosuppression Using the Calcineurin-Inhibitors Ciclosporin and Tacrolimus. Targeted Therapy with Imatinib: An Exception or a Rule? Clinical Aspects of Imantinib Therapy. Isoquinolinesulfonamide, a Specific Inhibitor of Rho-Kinase and the Clinical Aspect of Anti-Rho-Kinase Therapy. Discovery and Development of Iressa - The First in a New Class of Drugs Targeted at the Epidermal Growth Factor Receptor Tyrosine Kinase. eBook Springer 30.03.2006, Springer, Springer<
Nr. 24485740. Custos de envio:, Sofort per Download lieferbar, zzgl. Versandkosten. (EUR 16.85)
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Dados detalhados do livro - Inhibitors of Protein Kinases and Protein Phosphates
EAN (ISBN-13): 9783540266709 ISBN (ISBN-10): 3540266704 Ano de publicação: 2006 Editor/Editora: Springer Berlin 458 Páginas Língua: eng/Englisch
Livro na base de dados desde 2009-12-22T03:28:52-02:00 (Sao Paulo) Página de detalhes modificada pela última vez em 2023-02-11T08:18:16-03:00 (Sao Paulo) Número ISBN/EAN: 9783540266709
Número ISBN - Ortografia alternativa: 3-540-26670-4, 978-3-540-26670-9 Ortografia alternativa e termos de pesquisa relacionados: Autor do livro: born, pinna, lorenzo, cohen Título do livro: inhibitors protein, kina kina, handbook experimental pharmacology
Dados da editora
Autor: Lorenzo A. Pinna; Patricia T.W. Cohen Título: Handbook of Experimental Pharmacology; Inhibitors of Protein Kinases and Protein Phosphates Editora: Springer; Springer Berlin 458 Páginas Ano de publicação: 2006-03-30 Berlin; Heidelberg; DE Impresso / Feito em Língua: Inglês 523,23 € (DE) 537,90 € (AT) 590,00 CHF (CH) Available X, 458 p.
EA; E107; eBook; Nonbooks, PBS / Medizin/Pharmazie; Pharmakologie; Verstehen; Anticancer drugs; Antidiabetes targets; Calcineurin-Inhibitor; Cell signalling; Glycogen; Immunosuppressants; Signal transduction therapy; B; Pharmacology/Toxicology; Oncology; Pathology; Medical Biochemistry; Pharmacology; Oncology; Pathology; Medical Biochemistry; Biomedical and Life Sciences; Onkologie; Pathologie; Medizinische Chemie, Pharmazeutische Chemie; BB
Protein Kinase Inhibitors for the Treatment of Disease: The Promise and the Problems.- General Aspects of PKs Inhibition.- New Design Strategies for Ligands That Target Protein Kinase-Mediated Protein-Protein Interactions.- Pharmacological Potential and Inhibitors of Individual Classes of Protein Kinases.- The Paullones: A Family of Pharmacological Inhibitors of Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3.- Pharmacological Potential of p38 MAPK Inhibitors.- Inhibitors of PKA and Related Protein Kinases.- Inhibitors of Protein Kinase CK2: Structural Aspects.- Aminoglycoside Kinases and Antibiotic Resistance.- Pharmacological Potential and Inhibitors of Individual Classes of Protein Phosphatases.- Protein Tyrosine Phosphatases as Therapeutic Targets.- Structure-Based Design of Protein Tyrosine Phosphatase Inhibitors.- Biological Validation of the CD45 Tyrosine Phosphatase as a Pharmaceutical Target.- Serine/Threonine Protein Phosphatase Inhibitors with Antitumor Activity.- Inhibitors in Clinical Use or Advanced Clinical Trials.- Clinical Immunosuppression using the Calcineurin-Inhibitors Ciclosporin and Tacrolimus.- Targeted Therapy with Imatinib: An Exception or a Rule?.- Clinical Aspects of Imatinib Therapy.- Isoquinolinesulfonamide: A Specific Inhibitor of Rho-Kinase and the Clinical Aspect of Anti-Rho-Kinase Therapy.- Discovery and Development of Iressa: The First in a New Class of Drugs Targeted at the Epidermal Growth Factor Receptor Tyrosine Kinase.
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