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Recombinant Protein Production with Prokaryotic and Eukaryotic Cells. A Comparative View on Host Physiology : Selected articles from the Meeting of the EFB Section on Microbial Physiology, Semmering, Austria, 5th¿8th October 2000 - Otto-Wilhelm Merten
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Recombinant Protein Production with Prokaryotic and Eukaryotic Cells. A Comparative View on Host Physiology : Selected articles from the Meeting of the EFB Section on Microbial Physiology, Semmering, Austria, 5th¿8th October 2000 - Livro de bolso

2010, ISBN: 9048157560

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Recombinant Protein Production with Prokaryotic and Eukaryotic Cells. A Comparative View on Host Physiology - Herausgegeben:Merten, Otto-Wilhelm; Mattanovich, D.; Lang, C.; Larsson, G.; Neubauer, P.; Porro, D.; Postma, P.; Teixeira de Mattos, J.; Cole, J. A.
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Herausgegeben:Merten, Otto-Wilhelm; Mattanovich, D.; Lang, C.; Larsson, G.; Neubauer, P.; Porro, D.; Postma, P.; Teixeira de Mattos, J.; Cole, J. A.:

Recombinant Protein Production with Prokaryotic and Eukaryotic Cells. A Comparative View on Host Physiology - Livro de bolso

2010, ISBN: 9789048157563

[ED: Softcover], [PU: Springer / Springer Netherlands], More then 20 years have passed now since the first recombinant protein producing microorganisms have been developed. In the meanwhi… mais…

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Recombinant Protein Production with Prokaryotic and Eukaryotic Cells. A Comparative View on Host Physiology Selected articles from the Meeting of the EFB Section on Microbial Physiology, Semmering, Austria, 5th¿8th October 2000 - Merten, Otto-Wilhelm (Herausgeber); Mattanovich, D. (Herausgeber); Lang, C. (Herausgeber); Larsson, G. (Herausgeber); Cole, J. A. (Herausgeber); Porro, D. (Herausgeber); Postma, P. (Herausgeber); Teixeira de Mattos, J. (Herausgeber); Neubauer, P. (Herausgeber)
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Merten, Otto-Wilhelm (Herausgeber); Mattanovich, D. (Herausgeber); Lang, C. (Herausgeber); Larsson, G. (Herausgeber); Cole, J. A. (Herausgeber); Porro, D. (Herausgeber); Postma, P. (Herausgeber); Teixeira de Mattos, J. (Herausgeber); Neubauer, P. (Herausgeber):
Recombinant Protein Production with Prokaryotic and Eukaryotic Cells. A Comparative View on Host Physiology Selected articles from the Meeting of the EFB Section on Microbial Physiology, Semmering, Austria, 5th¿8th October 2000 - Livro de bolso

2010

ISBN: 9048157560

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Recombinant Protein Production with Prokaryotic and Eukaryotic Cells. A Comparative View on Host Physiology: Selected Articles From The Meeting Of The ... Semmering, Austria, 5th?8th October 2000
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Recombinant Protein Production with Prokaryotic and Eukaryotic Cells. A Comparative View on Host Physiology: Selected Articles From The Meeting Of The ... Semmering, Austria, 5th?8th October 2000 - Livro de bolso

2010, ISBN: 9789048157563

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Recombinant Protein Production with Prokaryotic and Eukaryotic Cells. A Comparative View on Host Physiology : Selected articles from the Meeting of the EFB Section on Microbial Physiology; Semmering; - Livro de bolso

2010, ISBN: 9048157560

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Recombinant Protein Production with Prokaryotic and Eukaryotic Cells. A Comparative View on Host Physiology: Selected Articles From The Meeting Of The ... Semmering, Austria, 5th?8th October 2000
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9789048157563


The general field of fundamental and applied biotechnology becomes increasingly important for the production of biologicals for human and veterinary use, by using prokaryotic and eukaryotic microorganisms. The papers in the present book are refereed articles compiled from oral and poster presentations from the EFB Meeting on Recombinant Protein Production with Prokaryotic and Eukaryotic Cells. A Comparative View on Host Physiology, which was organized in Semmering/A from 5th to 8th October 2000. A special feature of this meeting was the comparison of different classes of host cells, mainly bacteria, yeasts, filamentous fungi, and animal cells, which made obvious that many physiological features of recombinant protein formation, like cell nutrition, stress responses, protein folding and secretion, or genetic stability, follow similar patterns in different expression systems. This comparative aspect is by far the point of most interest because such comparisons are rarely done, and if they are done, their results are most often kept secret by the companies who generated them. Audience: Presently, a comparable book does not exist because the compiling of manuscripts from all fields of biotechnology (prokaryotic as well as eukaryotic, up to animal cell biotechnology) is not done in general. This particularity makes this book very interesting for postgraduate students and professionals in the large field of biotechnology who want to get a more global view on the current state of the expression of recombinant biologicals in different host cell systems, the physiological problems associated with the use of different expression systems, potential approaches to solve such difficulties by metabolic engineering or the use of other host cells, and the cooperation between process development and strain improvement, which is crucial for the optimisation of both the production strain and the process. This book should be in every library of an institution/organization involved in biotechnology.

Dados detalhados do livro - Recombinant Protein Production with Prokaryotic and Eukaryotic Cells. A Comparative View on Host Physiology: Selected Articles From The Meeting Of The ... Semmering, Austria, 5th?8th October 2000


EAN (ISBN-13): 9789048157563
ISBN (ISBN-10): 9048157560
Livro de capa dura
Livro de bolso
Ano de publicação: 2010
Editor/Editora: Merten, Otto-Wilhelm, Springer
412 Páginas
Peso: 0,607 kg
Língua: eng/Englisch

Livro na base de dados desde 2011-02-06T22:39:03-02:00 (Sao Paulo)
Página de detalhes modificada pela última vez em 2024-01-27T04:46:13-03:00 (Sao Paulo)
Número ISBN/EAN: 9789048157563

Número ISBN - Ortografia alternativa:
90-481-5756-0, 978-90-481-5756-3
Ortografia alternativa e termos de pesquisa relacionados:
Autor do livro: merten, larsson, lang wilhelm, von lang, matta, wilhelm otto, neubauer, teixeira, otto veh, heß otto
Título do livro: semmering, view beside, comparative physiology, 2000, october, microbial physiology, the host, wilhelm merten

Dados da editora

Autor: Otto-Wilhelm Merten; D. Mattanovich; C. Lang; G. Larsson; P. Neubauer; D. Porro; P. Postma; J. Teixeira de Mattos; J.A. Cole
Título: Recombinant Protein Production with Prokaryotic and Eukaryotic Cells. A Comparative View on Host Physiology - Selected articles from the Meeting of the EFB Section on Microbial Physiology, Semmering, Austria, 5th–8th October 2000
Editora: Springer; Springer Netherland
400 Páginas
Ano de publicação: 2010-12-01
Dordrecht; NL
Impresso / Feito em
Língua: Inglês
213,99 € (DE)
219,99 € (AT)
236,00 CHF (CH)
POD
X, 400 p.

BC; Hardcover, Softcover / Biologie/Biochemie, Biophysik; Biochemie; Verstehen; Bur; Codons; DNA; Fermentation; Mammalia; Metabolism; Oxidation; Translation; biotechnology; development; gene expression; genes; microorganism; proteins; transcription; biochemical engineering; Protein Biochemistry; Biochemistry; Microbiology; Animal Anatomy; Chemical Biology; Chemical Bioengineering; Mikrobiologie (nicht-medizinisch); Zoologie und Tierwissenschaften; Chemische Biologie; Biotechnologie; BB; EA

Cell-free translation systems.- Protein synthesis and co-translational folding in cell-free translation systems.- Metabolic burden and stress response.- The cellular response to unfolded proteins in the endoplasmic reticulum.- The effects of recombinant protein expression on the growth and metabolism of mammalian cells.- Mapping stresses in Escherichia coli to improve yield. Examining global gene regulation and « cell conditioning » strategies.- Cellular responses to strong overexpression of recombinant genes in Escherichia coli. DNA relaxation and cell death after induction of ?-glucosidase.- From Vitreoscilla hemoglobin (VHb) to a novel class of growth stimulating hemoglobin proteins.- Genetic stability and gene copy number effects.- Protein mass production in hybridomas and recombinant CHO cells.- Inducible gene copy number amplification for the production of heterologous proteins in Kluyveromyces lactis.- Antibiotic-free plasmid selection and maintenance in Bacteria.- Modelling of segregational plasmid instability of recombinant strain suspension of Escherichia coli.- Transcription, translation, and product formation in E. coli.- Production of optically pure aryl epoxides by recombinant E. coli carrying styrene monooxygenase. A new biocatalyst based on Pseudomonas fluorescens ST genes.- Translational problems associated with the rare arginine CGG in Escherichia coli. Frameshifhting at CGG codons.- Optimisation of the solubility of the recombinant Itk kinase domain in Escherichia coli.- Bacterial senescence and the oxidation paradox.- Metabolic approaches for the optimisation of recombinant fermentation processes.- Control and optimisation of cellular bottlenecks in recombinant protein production.- Expression and fermentation strategies for recombinant proteinproduction in Escherichia coli.- Transcription, translation, and product formation in microbial systems other than E. coli.- Overexpression of a Rhizopus oryzae lipase in Pichia pastoris strains containing multiple copies of the target gene.- Development of a heterologous gene expression system for use in Lactococcus lactis. A novel gram-positive expression system.- Metabolic network analysis for human therapeutic protein productions: effects of the P/O ratio.- Animal cell based expression systems — process optimisation.- Process-orientated metabolic engineering: cell lines with new properties in nutrient exploitation and protein glycosylation.- Influence of the metabolic status of packaging cells on retroviral vector production.- Optimizing the production of recombinant prion protein from CHO cells.- Recombinant protein production by transient transfection of suspension-growing cells.- Comparison of different microbial expression systems.- Production of recombinant human trypsinogen in Escherichia coli and Pichia pastoris. A comparison of expression systems.- Secretion of homologous and heterologous recombinant proteins in Escherichia coli and other gram-negative bacteria by using a new secretion system.- Monitoring of genes that respond to overproduction of insoluble recombinant proteins in Escherichia coli and Bacillus subtilis.- Model supported optimization of fed-batch fermentations for recombinant protein production.- Protease secretion capacity and performance analysis of recombinant Bacillus species.- Authors Index.
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