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Kamkin, Andre:

Mechanosensitivity and Mechanotransduction Andre Kamkin (u. a.) Buch Mechanosensitivity in Cells and Tissues Englisch 2010 - encadernada, livro de bolso

2010, ISBN: 9789048198801

[ED: Gebunden], [PU: Springer Netherland], This book presents the latest findings in the field of research of mechanosensitivity and mechanotransduction in different cells and tissues. Me… mais…

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Kamkin, Andre:

Mechanosensitivity and Mechanotransduction Andre Kamkin (u. a.) Buch Mechanosensitivity in Cells and Tissues Englisch 2010 - encadernada, livro de bolso

2010, ISBN: 9789048198801

[ED: Gebunden], [PU: Springer Netherland], This book presents the latest findings in the field of research of mechanosensitivity and mechanotransduction in different cells and tissues. Me… mais…

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Kamkin, Andre:
Mechanosensitivity and Mechanotransduction Andre Kamkin Buch Mechanosensitivity in Cells and Tissues Englisch 2010 - encadernada, livro de bolso

2010

ISBN: 9789048198801

[ED: Gebunden], [PU: Springer Netherland], This book presents the latest findings in the field of research of mechanosensitivity and mechanotransduction in different cells and tissues. Me… mais…

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ISBN: 9789048198801

This book presents the latest findings in the field of research of mechanosensitivity and mechanotransduction in different cells and tissues. Mechanosensitivity and mechanotransduction of… mais…

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Mechanosensitivity and Mechanotransduction - encadernada, livro de bolso

2010, ISBN: 9789048198801

Erscheinungsdatum: 12/2010, Medium: Buch, Einband: Gebunden, Titel: Mechanosensitivity and Mechanotransduction, Redaktion: Kamkin, Andre // Kiseleva, Irina, Verlag: Springer-Verlag GmbH /… mais…

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Mechanosensitivity and Mechanotransduction

This book presents the latest findings in the field of research of mechanosensitivity and mechanotransduction in different cells and tissues. Mechanosensitivity and mechanotransduction of the heart and vascular cells, in the lung, in bone and joint tissues, in sensor systems and in blood cells are described in detail. This Volume focuses on molecular mechanisms of mechanosensitivity and mechanotransduction via cytoskeleton. Integrin-mediated mechanotransduction, the role of actin cytoskeleton and the role of other cytoskeletal elements are discussed. It  contains a detailed description of several  stretch-induced signaling cascades with multiple levels of crosstalk between different pathways. It contains a description of the role of  nitric oxide in regulation of cardiac activity and in regulation of mechanically gated channels in the heart. In the heart mechanical signals are propagated into the intracellular space primarily via integrin-linked complexes, and are subsequently transmitted from cell to cell via paracrine signaling. Biochemical signals derived from mechanical stimuli activate both acute phosphorylation of signaling cascades, such as in the PI3K, FAK, and ILK pathways, and long-term morphological modii  cations via intracellular cytoskeletal reorganization and extracellular matrix remodelling. Cellular and molecular effects of mechanical stretch on vascular cells are also discussed. This Volume  highlights the role of mechanotransduction in the lung, in bone and joint tissues. For the first time mechanosensitivity and mechanotransduction in blood cells are discussed. It contains new insights into mechanosensitive K+ channels functioning in mouse B lymphocytes. This book is a unique collection of reviews outlining current knowledge and future developments in this rapidly growing field. Currently, investigations of the molecular mechanisms of mechanosensitivity and mechanotransduction are focused on several issues. The majority of studies investigate intracellular signaling pathways. Knowledge of the mechanisms which underlie these processes is necessary for understanding of the normal functioning of different organs and tissues and allows to predict changes, which arise due to alterations of their environment. Possibly such knowledge will allow the development of new methods of artificial intervention and therapies.  This book brings up the problem closer to the experts in related medical and biological sciences as well as practicing doctors besides just presenting the latest achievements in the field.

Dados detalhados do livro - Mechanosensitivity and Mechanotransduction


EAN (ISBN-13): 9789048198801
ISBN (ISBN-10): 9048198801
Livro de capa dura
Ano de publicação: 2010
Editor/Editora: Springer
371 Páginas
Peso: 0,731 kg
Língua: eng/Englisch

Livro na base de dados desde 2008-10-01T03:21:08-03:00 (Sao Paulo)
Página de detalhes modificada pela última vez em 2023-08-16T19:16:18-03:00 (Sao Paulo)
Número ISBN/EAN: 9789048198801

Número ISBN - Ortografia alternativa:
90-481-9880-1, 978-90-481-9880-1
Ortografia alternativa e termos de pesquisa relacionados:
Autor do livro: scholz, kiselev, andre


Dados da editora

Autor: Andre Kamkin; Irina Kiseleva
Título: Mechanosensitivity in Cells and Tissues; Mechanosensitivity and Mechanotransduction
Editora: Springer; Springer Netherland
371 Páginas
Ano de publicação: 2010-11-30
Dordrecht; NL
Impresso / Feito em
Língua: Inglês
213,99 € (DE)
219,99 € (AT)
236,00 CHF (CH)
POD
XXIV, 371 p.

BB; Hardcover, Softcover / Biologie/Mikrobiologie; Zellbiologie (Zytologie); Verstehen; Cytoskeleton; Mechanically gated channels; Mechanosensitivity; Mechanotransduction; Stretch-induced signaling cascades; Cell Biology; Medical Biochemistry; Human Physiology; Cardiology; Medizinische Chemie, Pharmazeutische Chemie; Physiologie; Kardiologie, Angiologie; BC

This book presents the latest findings in the field of research of mechanosensitivity and mechanotransduction in different cells and tissues. Mechanosensitivity and mechanotransduction of the heart and vascular cells, in the lung, in bone and joint tissues, in sensor systems and in blood cells are described in detail. This Volume focuses on molecular mechanisms of mechanosensitivity and mechanotransduction via cytoskeleton. Integrin-mediated mechanotransduction, the role of actin cytoskeleton and the role of other cytoskeletal elements are discussed. It  contains a detailed description of several  stretch-induced signaling cascades with multiple levels of crosstalk between different pathways. It contains a description of the role of  nitric oxide in regulation of cardiac activity and in regulation of mechanically gated channels in the heart. In the heart mechanical signals are propagated into the intracellular space primarily via integrin-linked complexes, and are subsequently transmitted from cell to cell via paracrine signaling. Biochemical signals derived from mechanical stimuli activate both acute phosphorylation of signaling cascades, such as in the PI3K, FAK, and ILK pathways, and long-term morphological modii  cations via intracellular cytoskeletal reorganization and extracellular matrix remodelling. Cellular and molecular effects of mechanical stretch on vascular cells are also discussed. This Volume  highlights the role of mechanotransduction in the lung, in bone and joint tissues. For the first time mechanosensitivity and mechanotransduction in blood cells are discussed. It contains new insights into mechanosensitive K+ channels functioning in mouse B lymphocytes. This book is a unique collection of reviews outlining current knowledge and future developments in this rapidly growing field. Currently, investigations of the molecular mechanisms ofmechanosensitivity and mechanotransduction are focused on several issues. The majority of studies investigate intracellular signaling pathways. Knowledge of the mechanisms which underlie these processes is necessary for understanding of the normal functioning of different organs and tissues and allows to predict changes, which arise due to alterations of their environment. Possibly such knowledge will allow the development of new methods of artificial intervention and therapies.  This book brings up the problem closer to the experts in related medical and biological sciences as well as practicing doctors besides just presenting the latest achievements in the field.
One book provides a detailed description of molecular mechanisms of mechanosensing and mechanotransduction in different cells One book brings together a comprehensive outline of modern vision of structure and functions of cytoskeleton Gives a wide and detailed coverage of mechanosensitive ion channels Provides a wide and detailed description of various signaling pathways

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